The role of amino acid electron-donor/acceptor atoms in host-cell binding peptides is associated with their 3D structure and HLA-binding capacity in sterile malarial immunity induction

► Fundamental residues located in some HABPs are associated with their 3D structure. ► Electron-donor atoms present in β-turn, random, distorted α-helix structures. ► Electron-donor atoms bound to HLA-DR53. ► Electron-acceptor atoms present in regular α-helix structure bound to HLA-DR52.