Time-imposed daily restricted feeding induces rhythmic expression of Fgf21 in white adipose tissue of mice

► Daily time-imposed restricted feeding induces rhythmic Fgf21 expression in white adipose tissue. ► Adipose Fgf21 expression is induced by refeeding followed by starvation, but not by continuous fasting. ► Fasting-induced hepatic Fgf21 expression is reversed by refeeding.