Delayed translocation of NGFI-B/RXR in glutamate stimulated neurons allows late protection by 9-cis retinoic acid

► NGFI-B and RXR translocate out of the nucleus after glutamate treatment. ► Arresting NGFI-B/RXR in the nucleus protects neurons from excitotoxicity. ► Late protection by 9-cis RA is possible due to a delayed translocation of NGFI-B/RXR.