Differential adenosine uptake in mixed neuronal/glial or purified glial cultures of avian retinal cells: Modulation by adenosine metabolism and the ERK cascade

► Mixed and glial cultures express ENTs with different pharmacological properties. ► Adenosine kinase is a main driving force for adenosine uptake in retinal cultures. ► Adenosine but not inosine is predominantly taken up by retinal cells in culture. ► Adenosine transport is modulated by the ERK cascade in retinal cultures.