An insight into the interaction mode between CheB and chemoreceptor from two crystal structures of CheB methylesterase catalytic domain

► We report the structure of Thermotoga maritima CheB methylesterase domain. ► We have compared the structure with the S. typhimurium CheB. ► Analysis indicates differing electrostatic surfaces near the catalytic region. ► We carry out computational docking using the two respective chemoreceptor structures. ► We thereby propose a CheB:chemoreceptor interaction mode.