Functional characterisation of Lp_2714, an EAL-domain protein from Lactobacillus plantarum

► Lp_2714 is shown to lack critical residues involved in the metabolism of cyclic-di-GMP. ► Lp_2714 is shown to lack phosphodiesterase activity. ► A model is proposed in which Lp_2714 acts as a sensor for cyclic-di-GMP. ► Associated genes are proposed to be involved in polysaccharide synthesis.