TNFα enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands

► TNFα, a proinflammatory cytokine, enhances the motility and invasiveness of prostate cancer cells. ► TNFα enhances the production of selectin ligands in prostate cancer cells, which results in increased binding to P-, E-, and L-selectins. ► TNFα upregulates the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands.