Asperlin induces G2/M arrest through ROS generation and ATM pathway in human cervical carcinoma cells

► A new anti-cancer effect of an antibiotics, asperlin, is exploited. ► Asperlin induced human cervical cancer cell apoptosis through ROS generation. ► Asperlin activated DNA-damage related ATM protein and cell cycle associated proteins. ► Asperlin could be developed as a new anti-cancer therapeutics.