Adipose tissue-deprived stem cells acquire cementoblast features treated with dental follicle cell conditioned medium containing dentin non-collagenous proteins in vitro

► In this study we examine the effects of dental follicle cell conditioned medium (DFCCM) containing dentin non-collagenous proteins (dNCPs) on differentiation of ADSCs. ► We examined that ADSCs treated with dNCPs/DFCCM underwent morphological changes and significantly lost their proliferative capacity. ► dNCPs/DFCCM enhanced the mineralization behaviour and mineralization-related marker expression of ADSCs. ► ADSCs acquired cementoblast features in vitro with dNCPs/DFCCM treatment.