Goose parvovirus structural proteins expressed by recombinant baculoviruses self-assemble into virus-like particles with strong immunogenicity in goose

► All three capsid proteins can be expressed in insect cells in baculovirus expression system. ► All three recombinant proteins were spontaneously self-assemble into virus-like particles whose size and appearance were similar to those of native purified GPV virions. ► The immunogenicity of GPV-VLPs was better than commercial inactivated vaccine and attenuated vaccine.