Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation

► HTT2800 has a significant effect on intracellular lipid accumulation. ► HTT2800 reduced muscle-specific genes and led to the emergence of adipocyte-related genes. ► HT2800 converts the differentiation pathway of C2C12 myoblasts to that of adipoblast-like cells.