Extracellular Nm23H1 stimulates neurite outgrowth from dorsal root ganglia neurons in vitro independently of nerve growth factor supplementation or its nucleoside diphosphate kinase activity

► Extracellular Nm23H1 stimulates nerve growth. ► Extracellular Nm23H1 provides pathfinding cues to growth cones. ► The neurotrophic activity of Nm23H1 is independent of NDP kinase activity. ► The neurotrophic activity of Nm23H1 is independent of NGF.