IM-412 inhibits transforming growth factor β-induced fibroblast differentiation in human lung fibroblast cells

► -A new molecule, IM-412, which showed an anti-fibrotic effect, was screened. ► -IM-412 decreased TGF-β-induced fibrotic markers. ► -IM-412 inhibits the overall TGF-β responses. ► -IM-412 may be a promising novel agent for anti-fibrosis.