Involvement of a centrosomal protein kendrin in the maintenance of centrosome cohesion by modulating Nek2A kinase activity

► Depletion of kendrin induces centrosome splitting. ► Kendrin associates with Nek2A kinase exhibiting considerably low activity. ► Nek2A kinase activity is suppressed by direct binding with kendrin. ► Expression of the Nek2A binding site suppresses the centrosome splitting at G2 phase.