کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10771095 | 1050838 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hepatoprotective and antioxidant effects of Morus bombycis Koidzumi on CCl4-induced liver damage
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Hepatoprotective and antioxidant effects of Morus bombycis Koidzumi on CCl4-induced liver damage Hepatoprotective and antioxidant effects of Morus bombycis Koidzumi on CCl4-induced liver damage](/preview/png/10771095.png)
چکیده انگلیسی
The antioxidant activity and liver protective effect of Morus bombycis Koidzumi were investigated. Aqueous extracts of M. bombycis Koidzumi had higher superoxide radical scavenging activity than other types of extracts. The aqueous extract at a dose of 100Â mg/kg showed significant hepatoprotective activity when compared with that of a standard agent. The biochemical results were confirmed by histological observations indicating that M. bombycis Koidzumi extract together with CCl4 treatment decreased ballooning degeneration. The water extract recovered the CCl4-induced liver injury and showed antioxidant effects in assays of FeCl2-ascorbic acid-induced lipid peroxidation in rats. Based on these results, we suggest that the hepatoprotective effect of the M. bombycis Koidzumi extract is related to its antioxidative activity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical and Biophysical Research Communications - Volume 329, Issue 3, 15 April 2005, Pages 991-995
Journal: Biochemical and Biophysical Research Communications - Volume 329, Issue 3, 15 April 2005, Pages 991-995
نویسندگان
Ying-Shan Jin, Jae-Hoon Sa, Tae-Heum Shim, Hae-Ik Rhee, Myeong-Hyeon Wang,