Effect of E1(64-81) hepatitis G peptide on the in vitro interaction of HIV-1 fusion peptide with membrane models

► Synthetic peptide E1(64-81) of Hepatitis G virus as possible inhibitor of HIV entry. ► E1(64-81) and HIV-1 fusion peptide (FP) forms a new specie when incubated together. ► E1(64-81) inhibits the action of HIV-1 FP on phospholipid monolayers. ► E1(64-81) reduces the interaction of HIV-1 FP with bilayers.