Fatty acid composition modulates sensitivity of Legionella pneumophila to warnericin RK, an antimicrobial peptide

► Growth phase modulates sensitivity to warnericin RK and fatty acid composition. ► Selection of an adapted strain, resistant to warnericin RK by selection pressure experiments. ► The adapted strain is more resistant and displays higher amount of BCFA. ► Two fatty acid associated genes were repressed in the adapted strain.