Small-angle neutron scattering studies of the effects of amphotericin B on phospholipid and phospholipid-sterol membrane structure

►Aamphotericin (AmB) causes an increase in thickness of POPC, and POPC-sterol membranes. ►The increase in membrane thickness is independent of AmB concentration and aggregation state. ►AmB appears to have the same effect on POPC-ergosterol and POPC-cholesterol membranes.