To the pore and through the pore: A story of mRNA export kinetics

► The co-transcriptional recruitment of mRNA maturation factors is linked to export. ► mRNPs have to undergo surveillance after transcription and before entry to the pore. ► mRNA transport rates per pore in yeast are about 16 mRNPs per minute. ► Docking and release are the rate-limiting steps of mRNA export through the pore. ► Translocation trough the nuclear pore occurs in tens of milliseconds.