کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10799318 1054312 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cloning and analysis of the murine Foxi2 transcription factor
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Cloning and analysis of the murine Foxi2 transcription factor
چکیده انگلیسی
Forkhead transcription factors comprise a large family of key regulators of embryonic development. Here, we describe the cloning and analysis of the murine Foxi2 gene, coding for a putative 311 amino acid protein resembling Foxi subfamily members in mice and other species. Expression analysis during the final stages of embryonic development revealed that Foxi2 expression is mainly confined to subsets of cells in epithelial structures and particular ducts, in addition to the developing forebrain and neural retina. Since FoxI factors are thought to be implicated in the regulation of cell fate, the highly restricted expression pattern of Foxi2 suggestive of a possible role in controlling cellular identity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression - Volume 1731, Issue 2, 10 November 2005, Pages 133-138
نویسندگان
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