FbpA - A bacterial transferrin with more to offer

► FbpA may be considered a structural and functional bacterial transferrin. ► The mechanism of FbpA mediated iron transport across the periplasm is described. ► FbpA is a naked iron carrier, a Fe-chel carrier, and a periplasmic binding protein. ► Studies reviewed here enhance understanding of human transferrin mechanisms. ► Studies reviewed here may provide approaches to the control of pathogenic diseases.