1α,25(OH)2-vitamin D3 stimulates rapid plasma membrane calcium influx via MAPK activation in immature rat Sertoli cells

► 1,25D3 stimulates Ca2+ influx in immature rat Sertoli cells. ► The Ca2+ influx is mediated by voltage-dependent Ca2+ channels, K+ and Cl− channels. ► The stimulatory effect of 1,25D3 depends on PKC, ERK1/2 and p38 MAPK pathways.