Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes

►8-Methyl-2′-dG accelerates parallel quadruplex formation in specific positions. ►Parallel quadruplexes are stabilized by a 8-methyl-2′-dG residue at 5′-end. ►8-Methyl-2′-dG promotes an all-syn tetrad in specific positions.