کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10820469 1060694 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
IMP-GMP 5′-nucleotidase in reptiles: Occurrence and tissue distribution in a crocodile and three species of lizards
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
IMP-GMP 5′-nucleotidase in reptiles: Occurrence and tissue distribution in a crocodile and three species of lizards
چکیده انگلیسی
IMP-hydrolyzing activity (which is reactive with goose anti-pig lung IMP-GMP 5′-nucleotidase (c-N-II: EC.3.1.3.5) serum) was detected in extracts from several tissues (liver, heart, kidney, spleen, stomach, lung and skeletal muscle) from constitutively uricotelic reptiles: a crocodile (Crocodylus siamensis), and three species of lizard (Furcifer oustaleti, Tupinambis rufescens and Varanus gouldi). The activities were markedly high in the livers: 3.0 units/g in the crocodile and 1.4-2.9 units/g in the lizards. These were similar to those previously reported for the livers from chicken and snakes (also constitutively uricotelic), and 4- to 10-fold higher than those in ammoniotelic or ureotelic vertebrates. These findings suggest that the high activity of IMP-GMP 5′-nucleotidase in the liver is a feature of constitutive uricotelism, and that the enzyme may participate in the production of uric acid as an end product of amino acid catabolism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology - Volume 142, Issue 1, September 2005, Pages 107-112
نویسندگان
, ,