The effects of phencyclidine (PCP) on anxiety-like behavior in the elevated plus maze and the light-dark exploration test are age dependent, sexually dimorphic, and task dependent

► Withdrawal from a single dose of PCP alters behavior in animal models of anxiety. ► Effects are age, sex and task dependent. ► In adults, PCP is anxiogeneic in males and anxiolytic in females in EPM and light dark test. ► In young adults, PCP is anxiogenic in the EPM and anxiolytic in the light dark test.