Anaplastic Lymphoma Kinase and Leukocyte Tyrosine Kinase: Functions and genetic interactions in learning, memory and adult neurogenesis

► Alk and Ltk are expressed throughout the mouse hippocampus. ► Mice lacking Alk have enhanced spatial memory. ► The enhanced spatial memory of Alk mutant mice is Ltk dependent. ► Alk and Ltk have partially redundant functions in adult neurogenesis.