Melamine induced cognitive impairment associated with oxidative damage in rat's hippocampus

► Examined rat's cognitive deficits induced by melamine in vivo ► MWM test, HE staining and ELISA methods were used. ► Melamine induces oxidative damage via affecting oxidation-antioxidation homeostasis. ► Neurotoxicology of melamine may produce morphological and energy metabolism changes.