Carbamazepine inhibits distinct chemoconvulsant-induced seizure-like activity in Dugesia tigrina

► (−)-Nicotine, picrotoxin, and NMDA induced seizure-like activity in planaria, Dugesia tigrina. ► Carbamazepine inhibited (−)-nicotine, picrotoxin, and NMDA induced pSLA. ► Oxcarbazepine, a carbamazepine derivative, antagonized (−)-nicotine induced pSLA.