Ethanol-induced sensitization depends preferentially on D1 rather than D2 dopamine receptors

► SCH-23390 and Sulpiride blocked ethanol's stimulant effects. ► SCH-23390 blocked the expression and the development of ethanol sensitization. ► Sulpiride did not block the ethanol sensitization once it had been induced. ► The neuroadaptations underlying ethanol sensitization depend on D1 receptors.