SSR181507, a dopamine D2 receptor and 5-HT1A receptor ligand: Evidence for mixed anxiolytic- and antidepressant-like activities

► SSR181507 is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist. ► SSR181507 has mixed antidepressant and anxiolytic activities. ► SSR181507 decreased the latency time to step-down in a passive avoidance task. ► SSR181507 reduced ultrasonic vocalization. ► SSR181507 potentiated social interaction.