Hyperphagia induced by sucrose: Relation to circulating and CSF glucose and corticosterone and orexigenic peptides in the arcuate nucleus

►Sucrose compared to starch preload increased food intake 60-120 min later. ►Serum and CSF glucose were elevated 10 min after sucrose vs starch preload. ►Serum and CSF glucose were suppressed 30-60 min after sucrose vs starch preload. ►NPY and AgRP in ARC were suppressed 10 min after sucrose vs starch preload. ►NPY and AgRP in ARC were elevated 30-60 min after sucrose vs starch preload.