کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10838320 | 1067115 | 2011 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Strain-specific outcomes of repeated social defeat and chronic fluoxetine treatment in the mouse
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
âºThe study illustrates how mouse strains differing in baseline emotionality respond to social defeat stress, thus highlighting strain-specific coping strategies. âºIn particular, C57BL6/J and BalbC mice showed predominant alterations supportive of metabolic and behavioral susceptibility, respectively. Strain-specific outcomes of a chronic fluoxetine treatment in several domains related to long-term stress responses and mood disturbances were also demonstrated. âºThis approach may provide a valid experimental tool to study different susceptibility levels to stress and vulnerability to its deleterious consequences, aiming at establishing a translational model with relevance for human pathology.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology Biochemistry and Behavior - Volume 97, Issue 3, January 2011, Pages 566-576
Journal: Pharmacology Biochemistry and Behavior - Volume 97, Issue 3, January 2011, Pages 566-576
نویسندگان
Maria Razzoli, Lucia Carboni, Michela Andreoli, Francesca Michielin, Alice Ballottari, Roberto Arban,