کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10838320 1067115 2011 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Strain-specific outcomes of repeated social defeat and chronic fluoxetine treatment in the mouse
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Strain-specific outcomes of repeated social defeat and chronic fluoxetine treatment in the mouse
چکیده انگلیسی
►The study illustrates how mouse strains differing in baseline emotionality respond to social defeat stress, thus highlighting strain-specific coping strategies. ►In particular, C57BL6/J and BalbC mice showed predominant alterations supportive of metabolic and behavioral susceptibility, respectively. Strain-specific outcomes of a chronic fluoxetine treatment in several domains related to long-term stress responses and mood disturbances were also demonstrated. ►This approach may provide a valid experimental tool to study different susceptibility levels to stress and vulnerability to its deleterious consequences, aiming at establishing a translational model with relevance for human pathology.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology Biochemistry and Behavior - Volume 97, Issue 3, January 2011, Pages 566-576
نویسندگان
, , , , , ,