Effects of the cannabinoid receptor agonist win 55,212-2 on operant behavior and locomotor activity in rats

These data show that administration of the synthetic cannabinoid receptor agonist WIN leads to dose-dependent alterations of the performance in an operant behavior task and of motor behavior. We confirm previous findings of dose-dependent motor stimulating and inhibiting effects of cannabinoids, and show an impairment of a complex operant behavior at higher doses of WIN.