کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10886806 1080054 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer
چکیده انگلیسی
Clear links between cancer and cellular signaling triggered by the insulin-like growth factor-I (IGF-I) receptor (IGF-IR) and its cognate ligands (IGF-I and IGF-II) have been reported throughout the past two decades. Experimental results suggest that the pharmaceutical targeting of this signaling pathway could be beneficial for the treatment of cancer. Here, more recent advances towards potentially clinically viable strategies to interfere with the function of IGF-IR will be discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug Discovery Today - Volume 10, Issue 15, 1 August 2005, Pages 1041-1047
نویسندگان
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