Capillary electrophoresis‐single strand conformation polymorphism for the detection of multiple mutations leading to tuberculosis drug resistance

► First report of CE-SSCP for the detection of mutations leading to TB drug resistance ► Explored optimum CE-SSCP conditions including polymer, temperature and voltage ► Noted separation polymer concentration affected choice of best polymer coating ► Simultaneous identification of mutations in 2 regions and non-TB causing mycobacteria ► Analysis complete in hours as opposed to the days-week for culturing samples