Carga de la enfermedad neumocócica invasora en los niños menores de 5 años en Cataluña (España) antes de la comercialización de la vacuna neumocócica conjugada heptavalente

The burden of pneumococcal disease (invasive and non invasive forms) in children under 5 years of age in Catalonia before the licensing of the 7-valent vaccine was substantial and, in the prevaccination era, was higher than that caused by other invasive disease-causing capsulated bacteria (Haemophilus influenzae type b, Neisseria meningitides serogroup C), whose vaccines are included in routine vaccination schedules.