Optimal assay design for determining the in vitro sensitivity of ring stage Plasmodium falciparum to artemisinins

- A novel synchronisation strategy for the production of tightly synchronised cultures of Plasmodium falciparum.
- A pulse assay mimicking clinical drug exposure that is optimised for testing short-lived drugs.
- An in vivo strategy for analysing artemisinin sensitivity that is relevant for studying artemisinin-resistant field strains.