کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10972593 1107264 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: An oestrogen-DNA adducts mediated pathway?
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: An oestrogen-DNA adducts mediated pathway?
چکیده انگلیسی
► The tumorigenic capacity of soluble egg antigens (SEA) of Schistosoma haematobium parasites was investigated. ► Schistosoma haematobium SEA increased the proliferation and decreased the apoptosis of urothelial cells in vitro. ► Schistosoma haematobium SEA increased oxidative stress and induced genotoxicity of urothelial cells in vitro. ► Mass spectrometry analysis identified catechol-oestrogens in S. haematobium SEA. ► An oestrogen-DNA adduct pathway to explain bladder carcinogenesis associated with S. haematobium infection is proposed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal for Parasitology - Volume 43, Issue 1, January 2013, Pages 17-26
نویسندگان
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