Ascaris lumbricoides pseudocoelomic body fluid induces a partially activated dendritic cell phenotype with Th2 promoting ability in vivo

►First study to examine dendritic cell (DC) maturation and function by Ascaris lumbricoides pseudocoelomic fluid (ABF). ►ABF induces a Th2 immune response in the absence of DC co-stimulatory marker expression. ►DC maturation induces extracellular signal regulated kinase and nuclear factor-κB intracellular signalling pathways independently of Toll-like receptor 4 TLR4.