کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11016692 | 1773883 | 2018 | 23 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Specific discrimination of gram-positive bacteria and direct visualization of its infection towards mammalian cells by a DPAN-based AIEgen
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
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چکیده انگلیسی
The infections caused by gram-positive bacteria (G+) is a major threat to public health due to their high morbidity and mortality, and the identification of G+ with high sensitivity and selectivity is urgently desirable. In this paper, a probe with aggregation-induced emission (AIE) characteristic is developed and used to discriminate G+ from other bacteria and fungus with excellent selectivity. Thanks for its AIE feature, this probe shows intense fluorescence when interacted with G+, and the signal can last for 24â¯h after incubating with S. aureus, which is benefit for long term tracing of translocation process with high contrast. Moreover, this probe can be used to visualize the infection processes of G+ towards mammalian cells, which provides valuable information for understanding the therapeutic mechanism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 187, December 2018, Pages 47-54
Journal: Biomaterials - Volume 187, December 2018, Pages 47-54
نویسندگان
Rong Hu, Fan Zhou, Taotao Zhou, Jianlei Shen, Zhiming Wang, Zujin Zhao, Anjun Qin, Ben Zhong Tang,