کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11018037 | 1720264 | 2018 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Carcinoma de células renales asociado a amplificación del gen TFEB. Presentación de un caso y revisión de la literatura
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
آسیبشناسی و فناوری پزشکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Renal carcinomas associated with translocation of transcription factors of the MiT/TFE family include, according to the latest World Health Organization classification, carcinomas with Xp11 translocation that involve the TFE3 gene and those with translocation t(6;11)(p21;q12) that affect the TFEB gene. Each one of these sub-types have well-defined clinicopathological and molecular characteristics. Currently, progress in molecular techniques has led to the description of neoplasms with molecular changes in these same genes but with alterations different to translocation. Thus, recently, cases have been published of TFEB-amplified renal carcinomas with prognoses that vary from cases associated with translocation and could therefore represent a new entity. We present a case of TFEB-amplified renal carcinoma with a full description of the clinicopathological characteristics and an updated revision of these neoplasms.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Española de PatologÃa - Volume 51, Issue 4, OctoberâDecember 2018, Pages 248-252
Journal: Revista Española de PatologÃa - Volume 51, Issue 4, OctoberâDecember 2018, Pages 248-252
نویسندگان
Carlos Mayoral Guisado, Áurea Gómez Durán, Dixan AgustÃn BenÃtez López, Weimar Toro Zambrano, Alejandro Rubio Fernández, Alicia Moreno Ontalba, Mario DÃaz Delgado,