کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11024087 1701185 2018 34 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adherence, insight and disability in paranoid schizophrenia
ترجمه فارسی عنوان
پایبندی، بینش و ناتوانی در اسکیزوفرنی پارانوئید
کلمات کلیدی
بینش، بصیرت، درون بینی، جنون جوانی، پایبندی به درمان، معلولیت،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
چکیده انگلیسی
Insight has long been linked to both prognosis and functioning in patients with schizophrenia; likewise, it is key to treatment adherence. This study seeks to assess the association between insight, adherence to pharmacological treatment, and disability in schizophrenia, and to study the potential mediating role of adherence between insight and disability. Insight (SUMD), adherence (CRS), and disability (WHO-DAS) were measured in 80 clinically stable patients with DSM-IV TR paranoid schizophrenia. Psychopathology was assessed with the Positive and Negative Syndrome Scale (PANSS). In a first step, predictors of disability were identified using linear regression to identify variables related to disability and further a mediation analysis was carried out. Negative symptoms, insight, and adherence account for 54.2% of the variance in disability. Negative symptoms act directly on disability, while the effect of insight on disability is partially mediated by adherence. Insight is key in disability in schizophrenia and should be leveraged in treatment programs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 270, December 2018, Pages 274-280
نویسندگان
, , , ,