Quantitative ultrasonometry for the diagnosis of osteoporosis in human skeletal remains: New methods and standards

The current study aims to develop a new methodology to assess bone quality in modern and ancient human skeletal remains using Quantitative Ultrasonometry, applied for the first time to a skeletal sample of known age-at-death and sex (Frassetto collection, University of Bologna). After the assessment of intra- and inter-observer reliability, new ultrasonometric standards based on the analysis of age-related and sex-related changes in bone quantity and quality were created, providing a reference point for the analysis of osteoporosis and bone loss in skeletal remains. The applicability of the method was tested in a medieval sample including both males and females. The low intra- and inter-observer errors suggest that the Phalangeal Ultrasonometry is a reliable and valid technique that can be applied to modern and ancient human skeletons.