کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11033583 | 1601700 | 2018 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Overall survival prediction in glioblastoma multiforme patients from volumetric, shape and texture features using machine learning
ترجمه فارسی عنوان
پیش بینی کلی بقا در بیماران چندگانه گلیوبلاستوما از ویژگی های حجمی، شکل و بافت با استفاده از یادگیری ماشین
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کلمات کلیدی
گلیوبلاستوما چند حالته، پیش بینی بقا، فراگیری ماشین، ویژگی های شکل،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
چکیده انگلیسی
Glioblastoma multiforme (GBM) are aggressive brain tumors, which lead to poor overall survival (OS) of patients. OS prediction of GBM patients provides useful information for surgical and treatment planning. Radiomics research attempts at predicting disease prognosis, thus providing beneficial information for personalized treatment from a variety of imaging features extracted from multiple MR images. In this study, MR image derived texture features, tumor shape and volumetric features, and patient age were obtained for 163 patients. OS group prediction was performed for both 2-class (short and long) and 3-class (short, medium and long) survival groups. Support vector machine classification based recursive feature elimination method was used to perform feature selection. The performance of the classification model was assessed using 5-fold cross-validation. The 2-class and 3-class OS group prediction accuracy obtained were 98.7% and 88.95% respectively. The shape features used in this work have been evaluated for OS prediction of GBM patients for the first time. The feature selection and prediction scheme implemented in this study yielded high accuracy for both 2-class and 3-class OS group predictions. This study was performed using routinely acquired MR images for GBM patients, thus making the translation of this work into a clinical setup convenient.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Oncology - Volume 27, Issue 4, December 2018, Pages 709-714
Journal: Surgical Oncology - Volume 27, Issue 4, December 2018, Pages 709-714
نویسندگان
Parita Sanghani, Beng Ti Ang, Nicolas Kon Kam King, Hongliang Ren,