کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1162950 1490915 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Application of pH-responsive poly(2-dimethyl-aminoethylmethacrylate)-block-poly(acrylic acid) coatings for the open-tubular capillary electrochromatographic analysis of acidic and basic compounds
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Application of pH-responsive poly(2-dimethyl-aminoethylmethacrylate)-block-poly(acrylic acid) coatings for the open-tubular capillary electrochromatographic analysis of acidic and basic compounds
چکیده انگلیسی


• A new type of stimuli-responsive polymeric coating for OT-CEC has been prepared.
• The Y-shaped copolymer enables EOF magnitude and direction to be easily adjusted.
• Acidic and basic compounds analysed under different pH and ionic strength conditions.
• EOF-driven separations achieved with organic solvent free buffer electrolytes.
• Excellent repeatability over many cycles of use in the OTC-CEC mode achieved.

A new type of stimuli-responsive polymeric (SRP) coating has been prepared for use in open tubular capillary electrochromatography (OT-CEC), by grafting poly(2-dimethylaminoethylmethacrylate)-block-poly(acrylic acid) (PDMAEMA-b-PAA) as a Y-shaped block copolymer with two dissimilar chain compositions onto the inner walls of aminopropyl-modified silica capillaries. The grafting process introduced weakly charged functional groups from the PAA and PDMAEMA, enabling the generation of electroendosmotic flow with magnitude and direction adjustable by changing the pH of the running buffer electrolyte. This stimuli-responsive PDMAEMA-b-PAA block copolymer was found to provide excellent resolution of various acidic and basic compounds, leading to efficient analyte separation. When operated in the OT-CEC mode, separation selectivities could be readily manipulated via differential contributions from chromatographic and electrophoretic mechanisms, simply by changing the pH or the ionic strength of the running buffer electrolyte.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 917, 21 April 2016, Pages 117–125
نویسندگان
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