کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1164627 | 1491001 | 2014 | 5 صفحه PDF | دانلود رایگان |
• A novel colorimetric strategy for lead ion detection has been established.
• The detection relies on DNAzyme functionalized gold nanoparticles.
• Target-induced cleavage can mediate assembly of graphene oxide.
• The method displays excellent performance for the detection of lead ion.
In this paper, we report a novel colorimetric strategy for the detection of small molecules by using Pb2+ ion as an example. In this strategy, DNAzyme duplex modified gold nanoparticles (GNPs) are designed to be unable to interact with graphene oxide (GO). However, in the presence of Pb2+, the substrate strand of the DNAzyme is cleaved at its cleavage site, resulting in the disassembly of the DNAzyme duplex modified GNPs into three parts, i.e., the 3′- and 5′-fragments of substrate strand and the DNAzyme strand modified GNPs. By taking advantage of the efficient cross-linking effect of ssDNA-GNPs to GO, colorimetric sensor for the detection of the metal ion can be fabricated with a detection limit of 100 pM, which is much lower than the previous reports. This colorimetric method has also been used for the determination of Pb2+ in the tap water of the local city and the water from a reservoir with satisfactory results, so it may have potential applications in the future.
Figure optionsDownload as PowerPoint slide
Journal: Analytica Chimica Acta - Volume 831, 11 June 2014, Pages 60–64