کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1165007 | 1491061 | 2013 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Mixture models for two-dimensional baseline correction, applied to artifact elimination in time-resolved spectroscopy Mixture models for two-dimensional baseline correction, applied to artifact elimination in time-resolved spectroscopy](/preview/png/1165007.png)
Baseline correction and artifact removal are important pre-processing steps in analytical chemistry. We propose a correction algorithm using a mixture model in combination with penalized regression. The model is an extension of a method recently introduced for baseline estimation in the case of one-dimensional data. The data are modeled as a smooth surface using tensor product P-splines. The weights of the P-splines regression model are computed from a mixture model where a datapoint is either allocated to the noise around the baseline, or to the artifact component. The method is broadly applicable for anisotropic smoothing of two-way data such as two-dimensional gel electrophoresis and two-dimensional chromatography data. We focus here on the application of the approach in femtosecond time-resolved spectroscopy, to eliminate strong artifact signals from the solvent.
Figure optionsDownload as PowerPoint slideHighlights
► Penalized regression with P-splines to estimate a two-dimensional surface.
► For images and applications where anisotropic smoothing is required.
► Provides powerful baseline correction procedure for two-dimensional data.
► To correct for coherent artifact signals in ultrafast time-resolved spectra.
Journal: Analytica Chimica Acta - Volume 771, 10 April 2013, Pages 7–13