Preparation of cobalt-tetraphenylporphyrin/reduced graphene oxide nanocomposite and its application on hydrogen peroxide biosensor

A novel cobalt-tetraphenylporphyrin/reduced graphene oxide (CoTPP/RGO) nanocomposite was prepared by a π–π stacking interaction and characterized by ultraviolet–visible absorption spectroscopy (UV–vis), Fourier transform infrared spectroscopy (FTIR) and electrochemical impedance spectroscopy (EIS). The CoTPP/RGO nanocomposite exhibited high electrocatalytic activity both for oxidation and reduction of H2O2. The current response was linear to H2O2 concentration with the concentration range from 1.0 × 10−7 to 2.4 × 10−3 mol L−1 (R = 0.998) at the reductive potential of −0.20 V and from 1.0 × 10−7 to 4.6 × 10−4 mol L−1 (R = 0.996) at the oxidative potential of +0.50 V. The H2O2 biosensor showed good anti-interfering ability towards oxidative interferences at the oxidative potential of +0.50 V and good anti-interfering ability towards reductive interferences at the reductive potential of −0.20 V.

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► CoTPP/RGO nanocomposite was prepared by a π–π stacking interaction.
► CoTPP/RGO showed electrocatalytic activity for both oxidation and reduction of H2O2.
► The high sensitivity was due to the synergy effect between CoTPP and RGO.
► The CoTPP/RGO electrode showed good anti-interfering ability.