A carbohydrate modified fluoride ion sensor and its applications

A new fluorescent probe for the detection of F− (TBA+ and Na+ salts) has been developed, which is based on a desilylation triggered chromogenic reaction in water. This probe exhibits excellent F− ion selectivity as well as significant color changes visible to the naked eye at the concentration of 1.5 mg L−1, the WHO recommended level of F− ions in drinking water. This new carbohydrate modified probe can be used directly in aqueous medium without using organic co-solvents. Furthermore, the probe presents high sensitivity and selectivity for the imaging of F− ions in HepG2 cells.

A new fluorescent probe which exhibits excellent F− ion selectivity as well as significant color changes visible to the naked eye has been developed. This new carbohydrate modified probe can be used directly for water samples and in bioimaging without using organic co-solvents.Figure optionsDownload as PowerPoint slideHighlights
► We provide a carbohydrate modified fluorescent probe with excellent F− selectivity.
► The probe shows visible color change at WHO recommended F− level in drinking water.
► F− detection is processed in aqueous medium without using any organic co-solvents.
► The probe presents high sensitivity and selectivity for F− imaging in HepG2 cells.