کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1168736 | 960603 | 2008 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Screening of anti-HIV-1 inophyllums by HPLC–DAD of Calophyllum inophyllum leaf extracts from French Polynesia Islands Screening of anti-HIV-1 inophyllums by HPLC–DAD of Calophyllum inophyllum leaf extracts from French Polynesia Islands](/preview/png/1168736.png)
Various pyranocoumarins, calophyllolide, inophyllums B, C, G1, G2 and P, from Calophyllum inophyllum (Clusiaceae) leaves of French Polynesia (Austral, Marquesas, Society and Tuamotu archipelagos) have been determined in 136 leaf extracts using a high pressure liquid chromatography-UV-diode array detection (HPLC–UV-DAD) technique. Results show a wide range in chemical composition within trees growing on eighteen islands. The use of multivariate statistical analyses (PCA) shows geographical distribution of inophyllums and indicate those rich in HIV-1 active (+)-inophyllums. Inophyllum B and P contents (0.0–39.0 and 0.0–21.8 mg kg−1, respectively) confirm the chemodiversity of this species within the large area of French Polynesia. The study suggests the presence of interesting chemotypes which could be used as plant source for anti-HIV-1 drugs.
Journal: Analytica Chimica Acta - Volume 624, Issue 1, 22 August 2008, Pages 147–153